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Shijun Wen Selected Research

Sulfonamides

1/2020New tranylcypromine derivatives containing sulfonamide motif as potent LSD1 inhibitors to target acute myeloid leukemia: Design, synthesis and biological evaluation.

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Shijun Wen Research Topics

Disease

28Neoplasms (Cancer)
04/2024 - 01/2013
7Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2022 - 01/2016
3Mitochondrial Diseases (Mitochondrial Disease)
10/2022 - 01/2017
3Colorectal Neoplasms (Colorectal Cancer)
01/2021 - 11/2015
3Alzheimer Disease (Alzheimer's Disease)
09/2020 - 10/2013
2Neoplasm Metastasis (Metastasis)
01/2024 - 01/2017
2Lung Neoplasms (Lung Cancer)
01/2023 - 08/2013
2Glioblastoma (Glioblastoma Multiforme)
04/2022 - 01/2020
2Glioma (Gliomas)
04/2022 - 01/2020
2Lymphoma (Lymphomas)
01/2021 - 01/2017
2Rheumatoid Arthritis
07/2019 - 01/2018
2Colonic Neoplasms (Colon Cancer)
07/2019 - 01/2017
2Leukemia
01/2019 - 01/2016
1Sarcoma (Soft Tissue Sarcoma)
01/2024
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2023
1Ovarian Neoplasms (Ovarian Cancer)
01/2023
1Hematologic Neoplasms (Hematological Malignancy)
12/2022
1Ataxia Telangiectasia (Louis Bar Syndrome)
01/2021
1Breast Neoplasms (Breast Cancer)
01/2021
1Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
01/2021
1Pathologic Processes
09/2020
1Neuroinflammatory Diseases
09/2020
1Inflammation (Inflammations)
09/2020
1Carcinogenesis
01/2020
1Glucosephosphate Dehydrogenase Deficiency
01/2019
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2017
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/2017
1Adenocarcinoma of Lung
01/2017
1Tuberculosis (Tuberculoses)
01/2016

Drug/Important Bio-Agent (IBA)

5Auranofin (Ridaura)FDA Link
01/2023 - 01/2018
4Reactive Oxygen Species (Oxygen Radicals)IBA
10/2022 - 01/2013
4Phosphotransferases (Kinase)IBA
04/2022 - 09/2020
3Adenosine Triphosphate (ATP)IBA
04/2024 - 11/2013
3GoldIBA
01/2023 - 01/2018
3EnzymesIBA
01/2023 - 06/2018
3Lysine (L-Lysine)FDA Link
12/2022 - 01/2018
3Therapeutic UsesIBA
04/2022 - 06/2018
2Doxorubicin (Adriamycin)FDA LinkGeneric
04/2024 - 01/2017
2Enhancer of Zeste Homolog 2 ProteinIBA
01/2023 - 01/2018
2Histones (Histone)IBA
12/2022 - 01/2018
2platinum 109IBA
04/2022 - 09/2020
2snake venom protein C activatorIBA
01/2022 - 01/2021
2Aurora Kinase AIBA
01/2022 - 01/2021
2Proteins (Proteins, Gene)FDA Link
01/2021 - 01/2021
2Transcription Factors (Transcription Factor)IBA
01/2021 - 06/2018
2Glutathione (Reduced Glutathione)IBA
06/2017 - 01/2017
11-phenyl-3,3-dimethyltriazene (PDT)IBA
01/2024
1Poly(ADP-ribose) Polymerase InhibitorsIBA
01/2024
1NanocapsulesIBA
01/2024
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
01/2024
1A73025IBA
01/2023
1Polycomb Repressive Complex 2IBA
01/2023
1Histone MethyltransferasesIBA
01/2023
1Antineoplastic Agents (Antineoplastics)IBA
10/2022
1Gold CompoundsIBA
10/2022
1Antirheumatic Agents (DMARD)IBA
10/2022
1antiglomerular basement membrane antibodyIBA
04/2022
1alpha-hydroxyglutarateIBA
01/2022
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
01/2022
1MLN 8237IBA
01/2021
18-hydroxyguanineIBA
01/2021
1tazemetostatIBA
01/2021
13- (1H- indazol- 5- yl)- N- propylimidazo(1,2- b)pyridazin- 6- amineIBA
01/2021
1Aconitate Hydratase (Aconitase)IBA
01/2021
1DNA (Deoxyribonucleic Acid)IBA
01/2021
1Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
01/2021
1LipidsIBA
01/2021
1Messenger RNA (mRNA)IBA
01/2021
1Stearoyl-CoA DesaturaseIBA
01/2021
1Cyclin-Dependent Kinases (cdk Proteins)IBA
01/2021
1Citric Acid (Citrate)FDA LinkGeneric
01/2021
1Ataxia Telangiectasia Mutated ProteinsIBA
01/2021
1protein kinase C gamma (PRKCG)IBA
09/2020
1GlucocorticoidsIBA
09/2020
1LipopolysaccharidesIBA
09/2020
1Glycogen Synthase (Synthase I)IBA
09/2020
1Tranylcypromine (Parnate)FDA LinkGeneric
01/2020
1SulfonamidesIBA
01/2020
1rheinIBA
01/2020
1Thioredoxin-Disulfide ReductaseIBA
01/2020
1Celecoxib (Celebrex)FDA Link
07/2019
1Drug CombinationsIBA
07/2019
1Indicators and Reagents (Reagents)IBA
01/2019
1fms-Like Tyrosine Kinase 3IBA
01/2019
1AntioxidantsIBA
01/2019
1TransketolaseIBA
01/2019
1Sorafenib (BAY 43-9006)FDA Link
01/2019
1IsotopesIBA
01/2019
1salinomycinIBA
03/2018
1ATP-Binding Cassette Transporters (ABC Transporters)IBA
01/2018
1phenethyl isothiocyanate (PEITC)IBA
06/2017
1PhalloidineIBA
01/2017
1Glyceraldehyde-3-Phosphate Dehydrogenases (GAPD)IBA
01/2017
1Protein Isoforms (Isoforms)IBA
01/2017
1CateninsIBA
01/2017
1Glutamine (L-Glutamine)FDA Link
01/2017
1pantothenate synthetaseIBA
01/2016

Therapy/Procedure

8Therapeutics
01/2024 - 11/2015
2Drug Therapy (Chemotherapy)
01/2017 - 11/2015
1Photochemotherapy (Photodynamic Therapy)
01/2024